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Treatment with fluoxetine upregulates expression of 5-HT 2B receptors (which is decreased by chronic stress) selectively in astrocytes, and not in neurones

In summary, this study provides first evidence that treatment of a model rodent adrenal cell line with steroid precursors/ metabolites promote ROS production, stimulate (activate) p38 MAPK and CREB phosphorylation and changed gene transcription of StAR, CYP11A1 and three major antioxidant enzymes