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DOI: Published: Publisher Name: Springer, Cham Print ISBN: 978-3-319-99592-2 Online ISBN: 978-3-319-99593-9 eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0) Keywords Bioactivation Biotransformation Conjugation CYP3A4 CYP450 Cytochrome P450 Drug biotransformation Drug disposition Drug elimination Drug metabolism Efflux transporters Enzyme induction Enzyme inhibition Functionalization reactions Glucuronide Liver Metabolite Personalized medicine Phase I reactions Phase II reactions Precision medicine Stratified medicine Synthetic reactions