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In addition, Kim et al

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The findings contribute to a broader understanding of how indole-based small molecules interact with hp GSTP1-1 and may serve as a starting point for future studies exploring structurally optimized derivatives or other indole-containing metabolites with enhanced inhibitory potential

Hepatotoxic substrates and metabolism Drugs are absorbed from the sinusoidal blood into hepatocytes via transporters located in the basolateral membrane