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450 A 2023 study examined data from 45,114 VTE patients in Sweden treated with warfarin, rivaroxaban, or apixaban and found those who received apixaban had a 38% lower rate of a major bleeding event than those treated with rivaroxaban during the first six months of treatment

A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways