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Description

Chemodynamic therapy is a new anticancer approach in which agents (e.g., nanozymes) are used to convert hydrogen peroxide (H 2 O 2 ) into damaging hydroxyl radicals ( OH) via a Fenton reaction (Wang et al

Q.ZhangC.TaoS

Therefore, both excessive activation and inhibition of Nrf2 may be detrimental to DOX-induced cardiomyopathy

Hydrogen peroxide can be subsequently transformed to H 2 O and O 2 through catalase and glutathione peroxidase, which is coupled to oxidation of glutathione (GSH)