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This state is mainly reflected in the peptide/protein oxidative modification

However, current studies are only beginning to determine the crucial role of fatty acid metabolism in ISCs, and the detailed mechanisms regulating fatty acids mobilization, catabolism, biosynthesis and transport in response to external stimuli remain largely unclear

H., & Carstairs, S

+)-Lipoic acid reduces mitochondrial unfolded protein response and attenuates oxidative stress and aging in an in vitro model of non-alcoholic fatty liver disease