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Studies consistently show that deficiencies in key minerals like selenium, zinc, and copper significantly compromise antioxidant defenses and increase vulnerability to oxidative damage across multiple body systems

Constitutive overexpression of the proto-oncogenes c-myb in Balb/c-3T3 cells increases expression of both IGF-1 and IGF-1R, at least partly through an increased transcriptional activity and in this way abrogates the requirement for IGF-1 in the growing media (Kim et al, 1996)

American Family Physician, 96(6), 384-389

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