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Some approaches reduce symptoms but do not improve tissue strength

Superoxide production and expression of nox family proteins in human atherosclerosis

These trials should incorporate standardized protocols and biomarker-driven patient stratification to enhance reproducibility and outcome precision (Mushtaq and Rohit, 2025)

Such alterations can potentially result in cell death or cancer, with the most common repair pathway in metazoans, non-homologous DNA end joining, being more mutagenic than homologous recombination-mediated repair [153]