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It has shown activity at very low doses (nanogram to microgram per kilogram) without demonstrable toxicity in animal studies [11]

Many patients begin with 4-8 week initial cycles to establish baseline response and assess sleep quality improvements, with protocols often extending to 12+ weeks for comprehensive sleep pattern restoration

Ji et al., 2024

Acknowledgments The authors would like to acknowledge the use of generative AI technology, specifically Scholar AI, based on OpenAI's GPT-4 architecture, for revising the grammar of this paper