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Similarly, consumption of grape and blueberry polyphenols and acute low/moderate doses of caffeine-free polyphenol rich coffeeberry extract improved cognitive performance and ameliorated mental fatigue in healthy adults during a sustained cognitive effort (Philip et al

Typically, the majority of ATP is generated through mitochondrial respiration, with anaerobic glycolysis contributing to 2% of total ATP production

Acetylcholine is responsible for mood regulation, psychomotor activity, and sleep (438), by activation of central muscarinic receptors, rather than nicotinic receptors (153)