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Tightness in the throat and chest can occur with B12 deficiency and it is commonly mislabelled as anxiety. The mechanism is neurological and autonomic, not psychological. Here is the clear biology you B 12 Injections, Energy Boost at Acupuncture Aventura Vitamin B12: A Review of Clinical Use and Efficacy Nutritional Medicine Institute Autonomic Nervous System Anatomy: Overview, Gross Anatomy, Cardiac and Vascular Regulation
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