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For instance, the Ames and Snell mice, which are deficient for GH signaling, and the little mice with a mutation in the growth hormone-releasing hormone receptor ( GHRHR ) gene, are typical long-lived mouse models

The molecular mechanisms of arsenic-induced cell transformation and apoptosis

The highest activity of LLO is observed at the acidic pH of the vacuole (pH 5.5), while at the neutral pH of the host cytoplasm this activity decreases (Schuerch et al., 2005