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In human breast cancer cells, DADS inhibited TNF--induced release of MCP-1, a chemokine that promotes tissue remodeling, angiogenesis, and metastasis (77)

PubMed Monti JM, Debellis J, Alterwain P, et al

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Nox2 activity in macrophages results in intraphagosomal formation of oxygen free radicals (O2 ) and O2 derived ROS, which is required to neutralize parasite proliferation and disrupt its differentiation in the early stage of infection