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Inhibition of ROS by GSH or its analogs has been reported to block HIV replication, whereas increased intracellular GSH levels have been shown to enhance African swine fever virus replication 156,157 , indicating that the effect of GSH on viral replication varies according to the virus type

So I think anybody can get Alzheimer's disease with any genotype if there's enough insulin resistance, if there's basically enough difficulty in getting glucose through pyruvate dehydrogenase and into the Krebs cycle

Commonly measured antioxidant enzymes include glutathione (GSH), total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD), while malondialdehyde (MDA) is often used as a marker of oxidative stress

For individuals whose primary challenge is overeating, this represents a significant limitation