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0.40% and beyond: Likely lethal blood alcohol level

Therefore, the new structures were designed by elongating the carboxylate chain and incorporating bulky hydrophobic groups

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For non-natural lysine derivatives required in drug research and development (such as chiral-centermodified, side-chainfunctionalized, or isotopically labeled lysines), fermentation methods are often inadequate and chemical synthesis or chemoenzymatic approaches must be employed