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According to protein structure predictions 23 , they also adopt the thioredoxin fold, which puts the putative active site, a CCMC/S or CCLC/S motif, at the beginning of helix 1 (shown exemplarily for ROXY9 in Fig

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Interestingly, the ES for exercise capacity/TTE was 0.4998, which was similar to the 2012 meta-analysis, but the ES for performance/TT outcomes was only 0.1078

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