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As a paradigm, Wu and co-workers integrated Au nanoclusters (Au NCs) with histidine to accomplish GSH exhaustive-prompted RT, denoted as Au NCs@His (Figure 7A) (Zhang et al., 2018)

Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

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105 STRO-002 has been evaluated in several trials (e.g., NCT03748186, NCT05200364) and more recently has advanced to late-stage clinical trials (e.g., NCT06555263, NCT05870748)