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PMID: 36999649 Int J Med Sci Accumulation of RIPK1 into mitochondria is requisite for oxidative stress-mediated necroptosis and proliferation in Rat Schwann cells

Because oxidative processes can alter cardiovascular disorders, they have the potential to deliver tremendous health and lifespan benefits

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Indeed, recent structural and single-molecule experiments have revealed that, although DCTN1 contains a dynein-binding motif, a stable interaction between the mammalian dynein motor and dynactin requires a cargo adaptor, which links the motor complex to the cargo 57,58