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Monitoring of Vitamin B 12 in Patients Prescribed Metformin Given the possible negative impact of metformin on vitamin B 12 levels, monitoring of the status of individuals receiving this treatment might appear prudent

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In particular, a variant of approximately 20 kDa originated by an alternative splicing is present in a rather constant 1:9 ratio, [10] while recently an additional variant of ~ 23-24 kDa has also been reported in post-exercise states at higher proportions

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