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Niacin inhibits and reverses hepatic steatosis, inflammation, and prevents fibrosis by reduction of oxidative stress, and inhibition of DGAT2 and other possible mechanisms. (6) NMN and NR Target NAD+ Processes In contrast, NMN and NR appear to take a more targeted approach to cellular health, influencing key processes like DNA repair, mitochondrial function, and overall cell health through enzymes that rely on NAD+ as a fuel source