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It plays integral roles in: Immune regulation Cancer suppression (anti-proliferative and pro-apoptotic signaling) Mitochondrial function and redox balance Hormonal feedback loops, including cortisol and estrogen/testosterone rhythms Aging diminishes melatonin output by up to 75%, leading to weaker circadian cues and downstream systemic dysfunction

Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

GHK-Cu is available via injection, microneedling protocol, or topical sourced from Florida-licensed compounding pharmacies, administered under provider supervision

If longer-term storage of reconstituted solution is needed, aliquot into single-use volumes and store at 20C