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It is most studied in localised tissue-repair models gastrointestinal, tendon, ligament and connective tissue

Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal

For example, plasma levels of RvD1 are markedly reduced in patients compared with those in healthy controls and show a negative correlation with disease severity, with further decreases observed during active disease [93]

Circulation of the BAs is highly dependent on transporting from the hepatocytes into biliary tracts, a process that is highly susceptible to perturbation from even minor liver damage indicating that they may be sensitive biomarkers of liver injury (Yamazaki et al