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While this remains to be assessed in a future study, it has been established in rat models of depression that sub-chronic pre-treatment in adulthood alone is sufficient to improve sucrose preference ( Our findings align with the observation of beneficial effects of acute and long-term NAC-treatment on deficits in the cognitive and negative symptom domains found with rodent models of schizophrenia, depression, or related neuropsychiatric conditions (summarized in Table 1

[DOI] [PubMed] [Google Scholar] 176.Yue P, Gao L, Wang X, Ding X, Teng J