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Physical or emotional trauma: Events such as car accidents or significant psychological stress can trigger the onset of fibromyalgia

The data described below reflect exposure to ALIMTA plus cisplatin in 839 patients in Study JMDB

This mechanistic link explains why oxidative stress can amplify SASP-mediated tissue damage, creating a self-reinforcing cycle of inflammation and cellular dysfunction.18 Senolytics reduce SASP not only by eliminating the senescent cells that produce high ROS but also by disrupting pro-survival signaling pathways that sustain SASP activity

Now, to be honest, I increased my volume, so I technically have less potential recovery, but that's a whole separate topic because of the interaction between stress and fatigue and all that