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Description

IL-7, which is essential for T cell development and balance, activates NF-B signaling via the PI3K/AKT pathway, upregulates the expression of monocyte chemotactic protein 1 (MCP-1) and cell adhesion molecule (CAM) in macrophages and human aortic endothelial cells, and plays an active role in atherosclerosis

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The first point to consider for an efficient therapeutic effect without too many side effects is the expression of appropriate target molecules at the cell surface of MB cells (196198)