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OATP 2-((carboxycarbonyl)amino)-5-((1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)-4,7-dihydro-5H-thieno(2,3-c)pyran-3-carboxylic acid - 2-((carboxycarbonyl)amino)-5-((4-fluoro-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)-4,7-dihydro-5H-thieno(2,3-c)pyran-3-carboxylic acid - 2-((carboxycarbonyl)amino)-5-((4-hydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)-4,7-dihydro-5H-thieno(2,3-c)pyran-3-carboxylic acid - 2-((carboxycarbonyl)amino)-5-((5-hydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl)-4,7-dihydro-5H-thieno(2,3-c)pyran-3-carboxylic acid - 2-(1-(2,4-dichlorobenzyl)-1H-imidazol-2-yl)-7-hydroxy-4H-chromen-4-one - 2-(1-(2,4-dichlorobenzyl)-1H-imidazol-4-yl)-7-hydroxy-4H-chromen-4-one - 2-(1-(2,4-dichlorobenzyl)-1H-imidazol-5-yl)-7-hydroxy-4H-chromen-4-one - 2-(1-(3-chlorobenzyl)-1H-imidazol-2-yl)-7-hydroxy-4H-chromen-4-one - 2-(1-(3-chlorobenzyl)-1H-imidazol-4-yl)-7-hydroxy-4H-chromen-4-one competitive inhibitor, the compound shows selectivity ratio (9.5fold) over T-cell protein tyrosine phosphatase (TCPTP)

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doi: 10.1016/j.clim.2021.108665