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The evolutions in the field of drug discovery open the way to a new generation of senolytic therapies, such as immunological approaches (CAR-T cells, Antibody-Drug Conjugated or vaccines), which require preliminary steps of research to identify markers specifically expressed on senescent cells, demonstrating promising specific effects

look for the RENEW program and various REDEFINE trials

Table 5 Genes relevant to DNA repair affected by GHK 4.7 GHK vs GHK-Cu 4.7 GHK vs GHK-Cu There are many studies that obtain significant results with copper-free GHK, but the copper chelator bathocuproine abolishes the GHK effects

J Trace Elem Med Biol (2018) 50:498507