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doi: 10.1111/ijfs.17297 286 SimSHKyoungChoiHNaSCHwangDIOhHBLimYTet al

155 At the molecular levels astrocytic switch to putrescine catabolism and GABA synthesis is linked to the urea cycle expressed in astrocytes and generally responsible for detoxification of brain ammonium

Thus, the significant increase in levels of 3-NT observed in the autism cerebellum and BA22 was not unexpected and is consistent with elevated superoxide production and aconitase inactivation