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While emerging evidence establishes ferroptosis as a pivotal mediator of SLE nephritis (LN) pathogenesislinking iron dyshomeostasis, immune cell dysfunction, and renal injuryand identifies GPX4 as a key regulatory checkpoint, several critical, insufficiently addressed research gaps persist

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Wetenschappelijke studies richten zich onder andere op celmigratie, fibroblastgerelateerde processen, angiogenese-gerelateerde mechanismen, cytoskeletorganisatie en intracellulaire signalering binnen gecontroleerde laboratoriummodellen

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Contraindicated in Leber's disease (B12 risk) 2

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