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Research indicates DSIP may help normalize disrupted circadian rhythms in subjects with shift work disorder, jet lag, or age-related sleep disturbances characterized by reduced slow-wave sleep

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In a murine model of DEP exposure, BALB/c mice intranasally exposed to DEPs followed by a DEP challenge had upregulation of lung-specific expression of Ym1 and Ym2 transcripts relative to that of mice that were not exposed nor similarly challenged 43

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With some exceptions, a small portion of proteins can interact with the 20S and be degraded through a ubiquitin-independent pathway [21]

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