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doi: 10.1016/j.molmet.2020.01.001 40 DingHGZhangJZhangFZhangSOChenXZLiangWQet al

One- to two-millimetre intestinal samples were fixed in 2% glutaraldehyde, 4% PFA and 2 mM CaCl 2 in 0.1 M sodium cacodylate buffer, pH 7.2, at room temperature for more than one hour, dehydrated in an acetone series, post-fixed in 1% osmium tetroxide and processed for Eponate 12 (Ted Pella) embedding

The wide range of therapeutic options may make it challenging to approach nutritional management of migraine in a clinical setting, so a pragmatic model that helps personalise interventions from clinical signs and symptoms and reliable biomarkers would be useful

Examples include homoarginine (r = 0.185, P = 1.17E-01)