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Moreover, analytical SEC suggests that SnCE1 Y212A is properly-folded, however, in contrast to non-acetylated SnCE1 C256A it elutes as sole monomer indicating the mutation affects the oligomeric state (Supplementary Fig

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Moreover, previous reports describing the biological effects of FGF-2 (basic FGF) on cortical or hippocampal neurons in vitro have demonstrated increases in both neuron survival and neurite outgrowth (Walicke et al., Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc