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All published BPC-157 research has been conducted in in vitro cell culture and animal models

Based on this basis, my team and I further developed a high-fidelity Cas13Y (hfCas13Y) with efficient editing and very low off-target activities, which was also published in Nature Biotechnology 2022, laying out the technical foundation of the CRISPR/Cas13 system for future clinical applications. About BRIGHT Trial (NCT06623279) This open-label, multicenter, Phase 1, dosing finding trial (an open-la B el, dose-escalation study for CRISPR/Cas13- R NA target I n G t H erapy for the T reatment of neovascular age-related macular degeneration, BRIGHT ) is designed to evaluate the safety and tolerability of high-fidelity CRISPR-Cas13 RNA-editing therapy targeting knock-down of VEGF-A mRNA (HG202) in patients with nAMD, affecting nearly 190 million people over the age of 60 worldwide

Thus, the exposure situation is similar to that of the present study

Failure of high-dose vitamin C (ascorbic acid) therapy to benefit patients with advanced cancer