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Colchicine is a natural alkaloid compound derived from Colchicum autumnale [27] that was initially used as an effective compound for the treatment of gout and familial Mediterranean fever (FMF), and its pharmacokinetics have been well studied [28]

Adibi M, Thomas AZ, Borregales LD, Merrill MM, Slack RS, Chen HC, Sircar K, Murugan P, Tamboli P, Jonasch E, Tannir NM , Matin SF, Wood CG, Karam JA

We have also shown evidence of the possible transfer of the formaldehyde sensitive nmlR regulon from pathogenic Neisseria to Haemophilus species

Inhibiting DNA methylation by 5-aza-2-deoxycytidine ameliorates atherosclerosis through suppressing macrophage inflammation