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Polarization toward the M1 phenotype is predominantly induced by IFN-, LPS, and TNF- (76)

Tsilioni I, Taliou A, Francis K, Theoharides TC

Another theory is the opioid excess theory, which suggests that gluten and casein peptides are metabolized in the intestine into structurally similar short-chain peptides called gluteomorphins and casomorphins in the behavioral problems seen in these children [16]