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This stabilization is achieved through the recruitment of effectors, such as HuR, which shield the bound mRNA from nucleolytic degradation

Notably, LH1 and LH2 (consisting of the splicing isoform LH2a and LH2b) are primarily associated with the major collagen types (I, II, and III), whereas LH3 is primarily associated with the minor collagen types ( e.g ., IV and V) (Gjaltema and Bank, 2017