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& Lemmon, M

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The cognitive impairment associated with long COVID not only disrupts the patients daily activities but also increases stress and diminishes quality of life, making brain fog one of the most distressing and debilitating neurologic symptoms of this disorder

The authors emphasized that these pharmacokinetic limitations result in low plasma and tissue concentrations of curcumin, necessitating formulation strategies such as adjuvants, nanoparticles, liposomes, or phospholipid complexes to improve its bioavailability and therapeutic efficacy across various disease models