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Intraneuronal accumulation of amyloid- peptides as the pathomechanism linking autism and its co-morbidities: epilepsy and self-injurious behavior - the hypothesis

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Husain MI, Strawbridge R, Stokes PR, Young AH

173 Therefore, malignant cells shift from undertaking mitochondrial oxidative phosphorylation (OXPHOS) to invoking the glycolysis pathway, even under normal oxygen conditions with full and proper mitochondrial functioning, creating a pseudohypoxic state known as the Warburg effect

Idiosyncratic (type B) injury occurs without warning, when agents cause non-predictable hepatotoxicity in susceptible individuals, which is not related to dose and has a variable latency period