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Yen K, Wan J, Mehta HH et al (2018) Humanin prevents age-related cognitive decline in mice and is associated with improved cognitive age in humans

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Betaine, by virtue of aiding in the remethylation of homocysteine, removes both toxic metabolites [homocysteine and S-adenosylhomocysteine], restores S-adenosylmethionine level, reverses steatosis, prevents apoptosis and reduces both damaged protein accumulation and oxidative stress