DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan building block Product Name Pomalidomide-C2-piperazine HCl Synonyms

Product Name Pomalidomide-C2-piperazine HCl Synonyms Pomalidomide-4'-C2-piperazine HCl CAS Number n/a Related CAS Molecular Formula C19H25Cl2N5O4 Molecular Weight 458

It has been predominantly used to develop a variety of green fluorescent peptides that can be excited with the 488 nm line of the Ar laser

exhibited longer fluorescence lifetimes than its non-sulfonated counterparts

Product Name Trametinib Synonyms CAS Number 871700-17-3 Related CAS Molecular Formula C26H23FIN5O4 Molecular Weight 615

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan building block Product Name Pomalidomide-C2-piperazine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC