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Description

Two factors compound: drug exposure scales with body weight (lighter body = more drug per pound), and physiological response varies by metabolic and cardiovascular phenotype

The main POF inducer is the reproductive system (10)

ATAC-sequencing A total of 50,000 HSCs were resuspended in ice-cold cryopreservation solution (50% FBS, 40% growth medium and 10% dimethylsulfoxide (DMSO))