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How fast should the dose be escalated

Interactions of GST polymorphisms in air pollution exposure and respiratory diseases and allergies

Studies looking at NR doses up to 2,000mg per day and NMN doses up to 1,200mg per day found no differences in adverse effects between intervention and placebo groups.31 4 In studies of higher doses that produced adverse effects, typical reactions included:32 Headache Dry mouth GI upset Muscle cramps or spasms As with many forms of vitamin B, NR can cause some flushing, and both NR and NMN can cause digestive upset

Source matters as much as selection: both peptides are available as 503A compounded medications from licensed pharmacies or as unregulated research chemicals online