Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC in particular

in particular

5-FAM is the purified single isomer of carboxyfluorescein

S)-AHPC-CO-C1-piperazine HCl Synonyms CAS Number 2417258-49-0 Related CAS Molecular Formula C28H42Cl2N6O4S Molecular Weight 629

CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCN)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE AHPC in particularSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to