Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) cp Product Name Thalidomide-O-acetamido-C5-OH Synonyms Thalidomide-4'-O-acetamido-C5-OH

Product Name Thalidomide-O-acetamido-C5-OH Synonyms Thalidomide-4'-O-acetamido-C5-OH CAS Number n/a Related CAS Molecular Formula C20H23N3O7 Molecular Weight 417

PEG2 linker enhances water solubility and provides spatial separation to minimize steric hindrance during binding interactions

Product Name DOTA-tris(t-Bu)ester-C3-acid Synonyms CAS Number n/a Related CAS Molecular Formula C32H59N5O9 Molecular Weight 657

For research use only

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) cp Product Name Thalidomide-O-acetamido-C5-OH Synonyms Thalidomide-4'-O-acetamido-C5-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine