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Rationale Behavioural interventions Primary care practitioner advice, individual or group counselling in person or by telephone from a trained cessation counsellor, mobile phone text messaging interventions, and self-help materials all provide at least a small benefit for smoking cessation (Appendix 1)

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The FDA and the National Institutes of Health recently published a paper outlining that while getting smokers to quit is the gold standard, it might consider therapies that prove clinically meaningful reductions in smoking. The Center for Drug Evaluation and Research is not just encouraging drug development in this space, an FDA official said during a public meeting in October to discuss the regulators evolving approach to approving smoking cessation therapies, we are in fact rolling out the red carpet and very strongly supporting it. The goal of this product is not to replicate the nicotine delivery of a cigarette, says Qnovia CEO Brian Quigley, because we're not trying to get people to use this forever. The design of the RespiRx was inspired by e-cigarettes and vapes but uses medical grade dosing to deliver a precise amount of nicotine every day over a 12-week program

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