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Smokers often turn to cigarettes to feel calm when they're stressed. And there are two reasons for this First, nicotine has an anxiolytic effect by increasing the neurochemical GABA, which Smokings Impact on Testosterone Levels Revealed How Does Smoking Affect Hormone Levels and Hormone Replacement Therapy? Effects of electronic smoking on daytime plasma cortisol levels and the possible ameliorating role of physical activity: a cross sectional study PMC

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