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While conventional cigarettes produce toxicants through the process of combustion, heated tobacco products primarily follow the thermal degradation of substrate constituents

teens vaped in 2017, up more than 10 percentage points from 1.5 percent in 2011, according to the CDC

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Where to Go from Here Where to Go from Here The central problem of premarket review is not, as Dobbins contends, that FDA has made it too difficult to get e-cigarettes to market, but that the agency has allowed so many manufacturers, particularly of flavored products, to market their products while avoiding the obligation to demonstrate, prior to reaching the market, that their e-cigarettes are appropriate for the protection of the public health. This regulatory holiday has caused, and continues to cause, great harm to public health