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Knowledge translation tools to support implementation of this guideline can be found on the task force website ( Monitoring and evaluation Clinician awareness of this guideline and use of the recommendations and menu to support shared decision-making are performance measures for this guideline

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[86] Nicotine is a parasympathomimetic stimulant [89] that binds to and activates nicotinic acetylcholine receptors in the brain, [90] which subsequently causes the release of dopamine and other neurotransmitters, such as norepinephrine, acetylcholine, serotonin, gamma-aminobutyric acid, glutamate, endorphins, [91] and several neuropeptides, including proopiomelanocortin-derived -MSH and adrenocorticotropic hormone

International Journal of Epidemiology 2003: volume 32, issue 5, pages 802 to 808 (registration and subscription required for full article)