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As mentioned above, nicotine selectively activates nicotinic acetylcholine receptors (nAChRs), particularly those containing the 42 and 7 subunits, which in turn modulate dopamine, glutamate, serotonin, gamma-aminobutyric acid (GABA), and acetylcholine pathways associated with enhanced cognitive processing

Angered smokers have hit back, with the director of smokers' lobby group Forest, Simon Clark, arguing the tax will disproportionately punish people from poorer backgrounds

These findings explain why many smoking cessation specialists recommend the patch as the baseline treatment and a faster-acting form to handle breakthrough cravings

I had to rethink everything, she explains