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Nicotine itself has been used in oral forms (lozenges, gum, sprays) for over 40 years and is our mainstay of smoking cessation support

For the retrospective analysis, we performed pairwise case-control matching, where each THC-positive sample was matched to two THC-negative samples, as determined by the presence/absence of 11-COOH-THC in the FF

To minimise information bias, subjects self-entered and electronically locked tobacco, alcohol and drug use, history of homelessness, and prison stay information on computer-assisted software, thus inaccessible to the interviewer